01 - Preheat oven to 375°F. Lightly grease a 9x13 inch baking dish with cooking spray or butter.
02 - Pat chicken breasts dry with paper towels. Season both sides generously with salt and black pepper. Arrange seasoned chicken in the prepared baking dish in a single layer.
03 - In a medium mixing bowl, combine mayonnaise (or Greek yogurt), 1/2 cup Parmesan cheese, garlic powder, onion powder, paprika, and dried parsley. Whisk until smooth and fully incorporated.
04 - Spread the sauce mixture evenly over the tops of each chicken breast, ensuring complete coverage. Use the back of a spoon to create an even layer.
05 - Sprinkle remaining 1/4 cup Parmesan cheese over the sauced chicken. Add breadcrumbs if using for extra crunch.
06 - Bake uncovered for 25-30 minutes until chicken reaches internal temperature of 165°F and the top is golden brown and bubbly.
07 - Remove from oven and let chicken rest for 5 minutes before serving to allow juices to redistribute. Garnish with additional parsley if desired.